By hand

Context #1

Mark: Hi Dave, how are you? Oh, why do you look so worried?

Dave: Yeah, I'm a little worried about pollution.

Mark: I know, Earth is suffering. Pollution is terrible! That's why I always have my bag made by hand with me. They are super cute and sustainable. 

Dave: You made my day! I'm going to buy it now!

Meaning: Made by human hands and handheld tools as opposed to a machine. 

Context #2

Michael: Hello, Ana! Would you like me to help you with the deliveries?

Ana: No, Michael! I'm sorry but my boss told me to deliver the message by hand.

Michael: That's fine! I just wanted to help!

Meaning: Something that is delivered "by hand" is delivered by a person and given directly to the person it is addressed to. 

http://idiomstudy.blogspot.com/